Wesley Memorial Church is a Methodist church in central Oxford, England. John and Charles Wesley studied in Oxford, and the congregation was founded in 1783. The present church building was completed in 1878.

Oxford’s first Methodist meeting house was a building on the east side of New Inn Hall Street. It is now numbered 32–34 and is part of Brasenose College. A plaque on the wall commemorates the fact that John Wesley preached there on 4 July 1783.

The congregation later moved to a second building on the west side of the street. This has since been and the site has been incorporated into St Peter’s College.

The present Gothic Revival building was started in 1877 and opened in October 1878. The architect Charles Bell designed it in a revival of Decorated Gothic. The building contractor was Joshua Symm. Henry Frith of Gloucester carved the capitals of the columns, which portray twelve different kinds of English plants.